Ramsey's Conor Cummins and Castletown's Chris Palmer are amongst a star-studded line-up for Saturday's Macau Grand Prix.
The first practice session takes place on Thursday morning with qualifying on Friday.
Other T.T. riders taking part include reigning Macau title-holder Steve Plater, John McGuinness, Ian Hutchinson, Cameron Donald, Guy Martin, Michael Rutter and Martin Finnegan.
Pictures - Conor Cummins and Chris Palmer
Senior players to feature in cup as injuries hit squad says Ravens boss
FC Isle of Man face Maghull in The Macron Cup
Boxing: Burden 'really desperate' to bring home titles
'The Grenade' taking on Shauna Browne in London on Sunday
Hockey: Vikings B looking to extend league lead in depleted fixture listÂ
No premier league action as players away with national sides
Rugby: Vagabonds host Dunkinfield
Two games postponed due to Storm Boelo