Onchan surprised Ayre United in the GH Corlett Woods Cup preliminary round.
Craig Marsh, Mark Burman, Gerard Colligon and Mark Rees were on target in a 4-2 home win.
Phil Quayle and Elliot Cureton replied for the Tangerines.
Douglas Athletic are up to fifth in JCK Division Two after an 8-1 thrashing of Braddan.
A Josh Green treble, a Liam Dawson double and further goals from Darren Shields, Andy Newton and Stuart Monks (penalty) secured the three points to lift them above Colby in the table.
FC Isle of Man and AFC Liverpool to meet in vital hunt for points
Both teams eager to move further clear of drop zone
Hockey: Cup finals double-header on the cards
Three Island national sides in EH Championship action this weekend
Rugby: Douglas to host Sandbach in big top-of-the-table clash
Vagabonds, Vagabonds Ladies and Ramsey all at home for final matches of 2025
Football: Prem title contenders Corinthians and Peel to meet
Big top-of-the-table clash at forefront of weekend clashes