Away games for Vagas and Ramsey
Douglas host leaders Vale of Lune at Port-e-Chee in North One West this afternoon.
The Manx side are one of only two teams to inflict defeat on Vale of Lune so far this term.
In the day's other rugby fixtures, the odds are stacked against South Lancashire and Cheshire Division Two outfit Vagabonds.
They're away at Liverpool Collegiate, while Ramsey travel to Old Parkonians in South Lancashire and Cheshire Division Three.
Cycling: Bostock nominated for national champion of the year
Manxman one of six riders on British Cycling shortlist
Football: Railway Cup hopefuls all maintain pace in premier league
Castletown stay four points clear atop Division 2
Rugby: Vagabonds Ladies stay top with another victory
Vagabonds men and Douglas also take respective wins on home soil
Hockey: Harlequins A beat rivals to close in on prem leaders
Bacchas B take important victory in battle for top-flight safety