In Saturday afternoon's Football, Sure Mobile Premier League leaders Peel defend a five point advantage over Champions St. George's albeit having played two games more.
The westerners travel south to seventh placed Colby, while Geordies go the short distance down Glencrutchery Road to struggling Corinthians.
St. Mary's are third on goal difference only and also hit the road with an away fixture at Ayre.
In CFS Division Two, table-toppers St. John's entertain Northern Athletic.
Castletown are three points behind and play the Police at Groves Road where third placed Pulrose face Foxdale on the neighbouring pitch.
Football: IoM women's team back in action this weekend
Triathlon: Will Draper victorious at Challenge Salou
Grant Thomson to race next week after new ankle diagnosis
National rugby sides to make long-awaited return this weekend