Onchan surprised Ayre United in the GH Corlett Woods Cup preliminary round.
Craig Marsh, Mark Burman, Gerard Colligon and Mark Rees were on target in a 4-2 home win.
Phil Quayle and Elliot Cureton replied for the Tangerines.
Douglas Athletic are up to fifth in JCK Division Two after an 8-1 thrashing of Braddan.
A Josh Green treble, a Liam Dawson double and further goals from Darren Shields, Andy Newton and Stuart Monks (penalty) secured the three points to lift them above Colby in the table.
Tributes paid to 'legend' Eric Bregazzi
Family confirms passing of major Manx sporting figure
Powerlifting: Isle of Man squad confirmed for 2026 Home Nations
Island will host event for the first time later this month
Badminton: Mixed starts for Island sides at county championships
Both teams claim a win and a loss on the road
Josh Brookes leaves DAO Racing
Australian claimed TT podium with team this year