Castletown or Rushen v Pulrose
Ramsey v St George's
Ayre v Peel
St Mary's v Laxey
The draw was made live on Manx Radio on Saturday evening.
Ties to be played Saturday, March 6.
Draw for Cu-Plas FA Cup quarter-finals
More from Isle of Man Sport
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Shooting: Winter series gets underway
Ward, Berg and Parr lead the way
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Cycling: Bostock nominated for national champion of the year
Manxman one of six riders on British Cycling shortlist
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Football: Railway Cup hopefuls all maintain pace in premier league
Castletown stay four points clear atop Division 2
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Rugby: Vagabonds Ladies stay top with another victory
Vagabonds men and Douglas also take respective wins on home soil