Castletown or Rushen v Pulrose
Ramsey v St George's
Ayre v Peel
St Mary's v Laxey
The draw was made live on Manx Radio on Saturday evening.
Ties to be played Saturday, March 6.
Draw for Cu-Plas FA Cup quarter-finals
More from Isle of Man Sport
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Football: Colby stun defending champions in Hospital Cup
Douglas High School Old Boys relegated from premier league during Saturday clashes
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Rugby: Douglas beaten in Regional 2 North West play-offs
Ramsey win final home game of their season against Congleton
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Spirited FC Isle of Man lose out at Padiham
Both sides finish the game with ten men after entertaining contest
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Hockey: IoM Women's Over-45's set for EH Championship semi-final
They could become second Island side to reach an EH final this season