Past champions will help celebrate its 70th
The 70th anniversary of the Southern 100 will be marked at this year's event.
Among other things, 18 past champions, some dating back to the 1960s will be there, with parade laps and talk shows in the fan zone in Castletown Square.
For the first time, the races will also be live screened on Wednesday, 9 July and Thursday, 10 July.
Southern 100 club member Boris Kitching says there will be some well-known names to look out for:
Roads will close for the first practice session around the Billown course on Monday at 6pm.
Planning application for onshore wind farm still being developed
Motorcyclist suffered fatal chest injuries in crash
Trial for trio accused of producing Class A drugs to Island
Too early for 'direct action' over cost-of-living concerns says chief minister