The Mountain Road is one way from Ramsey to Douglas for the duration of TT fortnight.
It was introduced at the Centenary TT in 2007, to try and eradicate head-on collisions.
Inspector Terry Stephen of the Roads Policing Unit says despite the change, people still need to drive and ride responsibly up there:
Amendments to Assisted Dying Bill approved by Tynwald
Bill will now be resubmitted for royal assent
Indoor play business makes 'very difficult decision' to close
All Land Play Centre faced 'many challenges'
No routine GP appointments Wednesday afternoon
Doctors attending education session
Last chance to submit nominations for local authority by-elections
Douglas, Ballaugh and Port St Mary looking for new board members