Almost £23,000-worth of drugs were seized in an operation at Ronaldsway Airport earlier this week.
The drugs, thought to be heroin, were found during an operation on Tuesday evening in which two local men were arrested on suspicion of importing with intent to supply a Class A drug.
The men from Ramsey are currently in police custody and inquiries are ongoing.
Police are calling it a "significant seizure"
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Low cloud and fog causing disruption at airport
Some services already delayed while one flight has been cancelled